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20 stories from Planck Standard. Latest: September 3, 2026.
Blocking EP2 on tissue-resident macrophages kept old mice lean, strong and able to run a maze. A drug version worked on animals already 22 months old.
Researchers compared 142 people with exceptional memory against 89 typical peers and found no genetic advantage — not in APOE, not in polygenic risk scores, not even in rare protective variants.
Buck Institute researchers report that neurons carrying the rare APOE2 variant accumulate less DNA damage and resist cellular aging — and that adding APOE2 protein protected high-risk APOE4 neurons too.
In a small trial, a daily spermidine supplement reversed several markers of immune aging and strengthened antibody responses — especially in the people who needed it most.
Texas A&M researchers report that coffee's polyphenols and diterpenes activate NR4A1, a receptor tied to stress response and healthy aging, with decaf working just as well as regular.
In a randomized study of adults living with HIV, semaglutide cut the pace of biological aging by 9%, the first clinical hint the blockbuster drug may touch aging itself.
A UCLA team discovered that a protein called NDRG1 builds up in old muscle stem cells and slams the brakes on repair. Switching it off makes aged cells act young again — but at a cost to their long-term survival.
Heliconius butterflies live up to three times longer than their close relatives — and one species shows almost no physical decline with age, a new Nature Communications study reports.
Research from the Center for BrainHealth challenges the assumption that cognitive decline is inevitable, finding that daily habits can strengthen the mind at any age.
Even for a president known for imposing his own reality on every situation, Trump has not outrun scrutiny over his advanced age.
A treatment that targets a “gerozyme” restored shock-absorbing cartilage in old mice and prevented arthritis after joint injuries, raising hopes of avoiding knee and hip replacements.
A topical dose of the senescence-clearing drug ABT-263 rejuvenated old skin in mice and closed wounds faster, pointing toward new treatments for surgery and chronic injuries in older adults.
A Hokkaido University team found that whether a cell with a doubled genome lives or dies depends on how the division error occurred, pointing to a possible vulnerability in recurring tumors.
Researchers used AI to analyze CT scans from tens of thousands of adults and found that people with healthier thymuses lived longer and had substantially lower risks of heart disease, cancer, and death.
UCSF study finds older adults with 'normal' but lower B12 levels show signs of slower thinking and brain damage.
Research from UC San Francisco suggests that "normal" B12 levels may not be sufficient to protect against cognitive decline and brain damage in older adults.
A six-year, $2.1 million NIH-funded study published in Aging and Disease identifies tristetraprolin as a master brake on the chronic, low-grade inflammation that researchers now call "inflammaging" — and shows that holding TTP at youthful levels reverses the visible effects of aging in elderly mice.
Synthetic aptamers screened from 100 trillion random sequences could finally let drugs destroy senescent cells without harming healthy tissue, opening a new front against Alzheimer's and arthritis.
Mice with transferred gene lived 4.4% longer and showed improved resistance to cancer, inflammation, and age-related diseases.
Leipzig University researchers identified a molecular receptor that controls bone formation and showed a new compound called AP503 can dramatically boost bone density in mice, pointing toward a new class of osteoporosis treatment.